[et_pb_section fb_built=”1″ fullwidth=”on” custom_padding_last_edited=”on|desktop” admin_label=”section” _builder_version=”3.22.3″ custom_padding_tablet=”50px|0|50px|0″ custom_padding_phone=”” transparent_background=”off” padding_mobile=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on”][et_pb_fullwidth_header title=”PROGRESS REPORT – 2018″ text_orientation=”center” content_max_width=”none” _builder_version=”3.16″ title_font_size=”46px” background_color=”#eaeaea” background_layout=”light” button_one_letter_spacing_hover=”0″ button_two_letter_spacing_hover=”0″ saved_tabs=”all” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”on” button_one_letter_spacing__hover=”0″ button_two_letter_spacing__hover_enabled=”on” button_two_letter_spacing__hover=”0″ button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|desktop” admin_label=”section” _builder_version=”3.22.3″ background_color=”#f7f7f7″ custom_padding_tablet=”50px|0|50px|0″ custom_padding_phone=”” transparent_background=”off” padding_mobile=”off” make_fullwidth=”off” use_custom_width=”off” width_unit=”on”][et_pb_row column_structure=”1_2,1_2″ admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/2018-COVERBIG.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”3.23″ max_width=”500px” animation_style=”slide” animation_direction=”left” animation_duration=”500ms” animation_intensity_slide=”10%” border_width_all=”0px” border_color_all=”#ffffff” border_style_all=”solid” sticky=”off” use_border_color=”on” border_style=”solid” always_center_on_mobile=”on”][\/et_pb_image][et_pb_image src=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/2018-COVERBIG.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”3.23″ max_width=”500px” animation_style=”slide” animation_direction=”left” animation_duration=”500ms” animation_intensity_slide=”10%” border_width_all=”0px” border_color_all=”#ffffff” border_style_all=”solid” sticky=”off” use_border_color=”on” border_style=”solid” always_center_on_mobile=”on”][\/et_pb_image][et_pb_image src=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/2018-COVERBIG.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”3.23″ max_width=”500px” animation_style=”slide” animation_direction=”left” animation_duration=”500ms” animation_intensity_slide=”10%” border_width_all=”0px” border_color_all=”#ffffff” border_style_all=”solid” sticky=”off” use_border_color=”on” border_style=”solid” always_center_on_mobile=”on”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_blurb title=”THE GOAL” use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
The progress report takes a fresh look at how biology changes its cells. It looks for biological rules, captures them with equations, and then uses the equations to see how biology solves the problems we create with our experiments.<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”THE PROBLEM” use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
Change in biology involves wide-scale realignments in the parts and connections that define new relationships of structure to function. To biology a change is a solution. Our problem is to figure out how biology does it.<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”THE INCENTIVE” use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
If biology defines change quantitatively as a function of both structure (morphology) and function (biochemistry), then understanding biological changes must require access to such functions.<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”THE STRATEGY” use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”3.0.87″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” border_style=”solid”]Since we already know from earlier reports that biology\u2019s rules can be expressed as R^2 = 1 equations, the rules of change are likely to act similarly.
\n[\/et_pb_blurb][et_pb_blurb title=”THE UNDERSTANDING” use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
Biological changes cannot be managed successfully within a reductionist vacuum. Comparing concentrations, for example, creates such a vacuum because it ignores the accompanying complexity needed to parse a change. The report uses equations to explain why morphology and biochemistry can succeed when working together, but often fail when working alone. In biology, a change is defined by its complexity.<\/p>\n
[\/et_pb_blurb][et_pb_blurb title=”THE SOLUTION” use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_divider show_divider=”off” disabled_on=”on|on|off” _builder_version=”3.2″ hide_on_mobile=”on”][\/et_pb_divider][et_pb_image src=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/2018-REPORT.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”3.23″ animation_style=”slide” animation_direction=”left” animation_duration=”500ms” animation_intensity_slide=”10%” border_width_all=”2px” border_color_all=”#ffffff” border_style_all=”solid” sticky=”off” use_border_color=”on” border_width=”2px” border_style=”solid” always_center_on_mobile=”on”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_divider show_divider=”off” disabled_on=”on|on|off” _builder_version=”3.2″ hide_on_mobile=”on”][\/et_pb_divider][et_pb_blurb title=”PROGRESS REPORT – 2018″ use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
The progress report addresses problems related to detecting biological changes.<\/p>\n
[\/et_pb_blurb][et_pb_button button_url=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/paper19.pdf” button_text=”VIEW REPORT” button_alignment=”center” _builder_version=”3.16″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_divider show_divider=”off” disabled_on=”on|on|off” _builder_version=”3.23.4″ height=”40px”][\/et_pb_divider][et_pb_image src=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/2018-APPENDIX.jpg” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”3.23″ animation_style=”slide” animation_direction=”left” animation_duration=”500ms” animation_intensity_slide=”10%” sticky=”off” border_style=”solid” always_center_on_mobile=”on”][\/et_pb_image][et_pb_divider show_divider=”off” disabled_on=”on|on|off” _builder_version=”3.23.4″ height=”40px” hide_on_mobile=”on”][\/et_pb_divider][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_divider show_divider=”off” disabled_on=”on|on|off” _builder_version=”3.23.4″ height=”40px”][\/et_pb_divider][et_pb_blurb title=”APPENDIX FOR 2018″ use_icon=”on” font_icon=”%%61%%” icon_color=”#ffffff” use_circle=”on” circle_color=”#2ea3f2″ icon_placement=”left” _builder_version=”4.6.6″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” text_orientation=”center” hover_enabled=”0″ border_style=”solid” sticky_enabled=”0″]<\/p>\n
The appendix includes calculations associated with the figures in the report.<\/p>\n
[\/et_pb_blurb][et_pb_button button_url=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/report19_appendix.pdf” button_text=”VIEW INSTRUCTIONS” button_alignment=”center” _builder_version=”3.16″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_button][et_pb_button button_url=”https:\/\/playingcomplexitygames.com\/wp-content\/uploads\/2018\/01\/Change_structuretofunction_19.xlsx” button_text=”DOWNLOAD FILES” button_alignment=”center” _builder_version=”3.16″ button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”3.22.3″][et_pb_row admin_label=”row” _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.3″][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22.3″][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat”][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
The progress report takes a fresh look at how biology changes its cells. It looks for biological rules, captures them with equations, and then uses the equations to see how biology solves the problems we create with our experiments. Change in biology involves wide-scale realignments in the parts and connections that define new relationships of […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-2563","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=\/wp\/v2\/pages\/2563","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2563"}],"version-history":[{"count":14,"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=\/wp\/v2\/pages\/2563\/revisions"}],"predecessor-version":[{"id":2818,"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=\/wp\/v2\/pages\/2563\/revisions\/2818"}],"wp:attachment":[{"href":"https:\/\/playingcomplexitygames.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2563"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}